oh this is cool i have done it before i have a 4gb memory stick running windows vista beta yes i got the beta its really cool you plug card into the usb turn the computer on and get it to run from the memory pen and there you go you got windows but it is limited in its usage!
what do you mean for like storing music and pictures to be viewed on the 360 because you can just plug it into the usb to do that but im sorry i don't think its passable to use it a HDD to store game data and profiles ect on but i might be wrong..